Author's response to reviews Title: Intensified Neoadjuvant Radiochemotherapy for Rectal Cancer Enhances Surgical Complications Authors:
نویسندگان
چکیده
Leif Schiffmann ([email protected]) Nicole Wedermann ([email protected]) Michael Gock ([email protected]) Friedrich Prall ([email protected]) Gunther Klautke ([email protected]) Rainer Fietkau ([email protected]) Bettina Rau ([email protected]) Ernst Klar ([email protected])
منابع مشابه
Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications
BACKGROUND Neoadjuvant radiochemotherapy has proven superior to adjuvant treatment in reducing the rate of local recurrence without impairing cancer related survival or the incidence of distant metastases. The present study aimed at addressing the effects of an intensified protocol of neoadjuvant treatment on the development of postoperative complications. METHODS A total of 387 patients unde...
متن کاملNew drug in neoadjuvant chemoradiation for rectal cancer
Background: In recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. In this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...
متن کاملTitle: Prognosis of Rectal Cancer Patients Improves Analog to Downstaging by Intensified Neoadjuvant Radiochemotherapy -a Matched Pair Analysis
Leif Schiffmann ([email protected]) Gunther Klautke ([email protected]) Nicole Wedermann ([email protected]) Michael Gock ([email protected]) Friedrich Prall ([email protected]) Rainer Fietkau ([email protected]) Bettina M Rau ([email protected]) Ernst Klar ([email protected]...
متن کاملIntensified neoadjuvant radio-chemotherapy for locally advanced rectal cancer: mono-istitutional experience and long-term results
Background: Purpose: The purpose of our study is to demonstrate that intensified neoadjuvant chemo-radiotherapy (CRT) treatment in locally advanced rectal cancer (LARC), aimed at further enhancing the complete pathological response and local disease control, is feasible and well tolerated. Materials and Methods: From January 2011 to December 2015, 62 patients (women 21, men 41, mean age 61,5, ...
متن کاملDiffusion-Weighted Magnetic Resonance Application in Response Prediction before, during, and after Neoadjuvant Radiochemotherapy in Primary Rectal Cancer Carcinoma
INTRODUCTION Our interest was to monitor treatment response using ADC value to predict response of rectal tumour to preoperative radiochemotherapy. MATERIALS AND METHODS Twenty-two patients were treated with long course of radiochemotherapy, followed by surgery. Patients were examined by diffusion-weighted imaging MRI at three-time points (prior, during, and after radiochemotherapy) and were ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012